Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
| ▸ | POLQ | O75417 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038462 | 0.85 | MAPT (0.40) | SMN1; SMN2NOTUMMAPTMLYCDNR1H3 | |
| SCHEMBL2903315 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2NOTUMMAPTMLYCDNR1H3 | |
| SCHEMBL486173 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTLMNAHTTPOLB | |
| SCHEMBL6861323 | 0.72 | KMT2A (0.36) | SMN1; SMN2MAPTLMNAHTTNPSR1 | |
| SCHEMBL5404611 | 0.71 | PLAU (0.33) | SMN1; SMN2MAPTPOLBALDH1A1KMT2A | |
| SCHEMBL2483553 | 0.71 | POLB (0.32) | SMN1; SMN2MAPTMLYCDPOLBALDH1A1 | |
| SCHEMBL3073313 | 0.70 | KMT2A (0.49) | SMN1; SMN2MLYCDLMNAPOLBALDH1A1 | |
| SCHEMBL2535672 | 0.68 | PGR (0.41) | SMN1; SMN2NOTUMLMNAHTTNPSR1 | |
| SCHEMBL5516357 | 0.68 | KMT2A (0.38) | SMN1; SMN2MAPTPOLQLMNAMEN1 | |
| SCHEMBL9490747 | 0.68 | ROCK2 (0.47) | SMN1; SMN2NOTUMMAPTMLYCDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | SMN1; SMN2 2519/4885NOTUM 945/4885MAPT 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.