SCHEMBL9490747

SCHEMBL9490747

CNC(=O)N(C)c1cc[c]cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.47
LMNA P02545 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PKM P14618 1/20 0.37
CYP3A4 P08684 1/20 0.34
SMN1; SMN2 Q16637 4/20 0.33
RAB9A P51151 3/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
MLYCD O95822 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HTT P42858 2/20 0.31
NOTUM Q6P988 1/20 0.31
MAPT P10636 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
TP53 P04637 1/20 0.30
IMPDH2 P12268 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9408595 0.85 ROCK2 (0.59) ROCK2LMNAL3MBTL1PKMCYP3A4
SCHEMBL10344582 0.79 NOTUM (0.35) ROCK2PKMSMN1; SMN2RAB9AKDM4E
SCHEMBL8946061 0.79 LMNA (0.59) ROCK2LMNAL3MBTL1PKMSMN1; SMN2
SCHEMBL137254 0.79 LMNA (0.59) ROCK2LMNAL3MBTL1PKMSMN1; SMN2
SCHEMBL5472838 0.78 ROCK2 (0.30) ROCK2
SCHEMBL5481193 0.78 ROCK2 (0.30) ROCK2
SCHEMBL6969361 0.78 ROCK2 (0.40) ROCK2LMNAL3MBTL1PKMCYP3A4
SCHEMBL5814273 0.78 ROCK2 (0.53) ROCK2LMNAL3MBTL1CYP3A4SMN1; SMN2
SCHEMBL486173 0.77 SMN1; SMN2 (0.47) LMNASMN1; SMN2RAB9ANPC1ALDH1A1
SCHEMBL6861323 0.77 KMT2A (0.36) LMNAL3MBTL1PKMSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4927734-A CONTAINING A FORMYLHYDRAZINOPYRIDINE COMPOUND DAINIPPON INK. AND CHEMICALS, INC. (JP) 1990-05-22 US claimed
EP-0322553-A1 Silver halide photographic light-sensitive material and a process for forming a high contrastphotographic image DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-07-05 EP claimed
EP-0322553-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND A PROCESS FOR FORMING A HIGH CONTRASTPHOTOGRAPHIC IMAGE DAINIPPON INK AND CHEMICALS, INC. (JP) 1993-01-27 EP disclosed
US-4927734-A CONTAINING A FORMYLHYDRAZINOPYRIDINE COMPOUND DAINIPPON INK. AND CHEMICALS, INC. (JP) 1990-05-22 US disclosed
EP-0322553-A1 Silver halide photographic light-sensitive material and a process for forming a high contrastphotographic image DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-07-05 EP disclosed