Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 9/20 | 1.00 |
| ▸ | MAOB | P27338 | 4/20 | 0.77 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21169395 | 1.00 | MIF (1.00) | MIFMAOBCYP26A1CYP19A1PKM | |
| SCHEMBL14033869 | 0.87 | MAOB (0.81) | MIFMAOBCYP26A1CYP19A1PKM | |
| SCHEMBL29546151 | 0.87 | MAOB (1.00) | MIFMAOBCYP19A1PKMCYP11B2 | |
| SCHEMBL980327 | 0.87 | MAOB (1.00) | MIFMAOBCYP19A1PKMCYP11B2 | |
| SCHEMBL15153677 | 0.87 | MAOB (1.00) | MIFMAOBCYP19A1PKMCYP11B2 | |
| SCHEMBL29546087 | 0.87 | MAOB (1.00) | MIFMAOBCYP19A1PKMCYP11B2 | |
| SCHEMBL820654 | 0.87 | MAOB (1.00) | MIFMAOBCYP19A1PKMCYP11B2 | |
| SCHEMBL29679848 | 0.87 | MAOB (1.00) | MIFMAOBCYP19A1PKMCYP11B2 | |
| SCHEMBL7701204 | 0.86 | MIF (1.00) | MIFMAOBCYP19A1KMT2AMEN1 | |
| SCHEMBL7002746 | 0.86 | MIF (1.00) | MIFMAOBCYP19A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230457-B | 2-benzylidene tetralone derivatives, and preparation method and application thereof | 中山大学 | 2023-06-09 | — | — | CN | disclosed |