Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30442837 | 1.00 | GAA (0.61) | GAAKDM4EALDH1A1IDH1P2RX3 | |
| SCHEMBL15213071 | 0.79 | P2RX3 (0.43) | GAAKDM4EALDH1A1IDH1P2RX3 | |
| SCHEMBL29014110 | 0.79 | MERTK (0.53) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2276202 | 0.78 | ALDH1A1 (0.61) | GAAKDM4EALDH1A1IDH1SCN9A | |
| SCHEMBL12407368 | 0.77 | KDM4E (0.71) | GAAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL29642859 | 0.76 | GAA (1.00) | GAAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL13610402 | 0.76 | GAA (1.00) | GAAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL202821 | 0.75 | AR (0.42) | GAASCN9ATBXA2RSMN1; SMN2ACP1 | |
| SCHEMBL3665143 | 0.75 | KDM4E (0.59) | GAAKDM4EALDH1A1GLAMAPT | |
| SCHEMBL105821 | 0.74 | ALDH1A3 (0.47) | GAAALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217490-A | Benzimidazole compound, and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-06-06 | — | — | CN | disclosed |