Biphenyl

Biphenyl

SCHEMBL2901532

CC(=O)Cl.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.61
MAPT P10636 2/20 0.61
ALDH1A1 P00352 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.48
PTGS2 P35354 1/20 0.48
ABCC4 O15439 1/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 1/20 0.46
PTGS1 P23219 1/20 0.46
HTT P42858 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
CYP1A2 P05177 1/20 0.46
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
HPGD P15428 1/20 0.45
KMO O15229 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28188056 0.88 MMP3 (0.68) SMN1; SMN2MAPTLMNACES2MMP3
Biphenyl SCHEMBL3399859 0.88 ALDH1A1 (0.60) SMN1; SMN2MAPTALDH1A1L3MBTL1PTGS2
Biphenyl SCHEMBL538359 0.88 SMN1; SMN2 (0.67) SMN1; SMN2MAPTALDH1A1L3MBTL1PTGS2
Biphenyl SCHEMBL15332958 0.88 SMN1; SMN2 (0.67) SMN1; SMN2MAPTALDH1A1L3MBTL1PTGS2
Biphenyl SCHEMBL1822628 0.88 SMN1; SMN2 (0.67) SMN1; SMN2MAPTALDH1A1L3MBTL1PTGS2
Biphenyl SCHEMBL7062651 0.88 ALDH1A1 (0.60) SMN1; SMN2MAPTALDH1A1L3MBTL1PTGS2
Biphenyl SCHEMBL5071211 0.88 ALDH1A1 (0.60) SMN1; SMN2MAPTALDH1A1L3MBTL1PTGS2
Biphenyl SCHEMBL29059196 0.88 SMN1; SMN2 (0.67) SMN1; SMN2MAPTALDH1A1L3MBTL1PTGS2
Biphenyl SCHEMBL10587144 0.85 SMN1; SMN2 (0.64) SMN1; SMN2MAPTALDH1A1L3MBTL1PTGS2
Biphenyl SCHEMBL8025407 0.85 SMN1; SMN2 (0.64) SMN1; SMN2MAPTALDH1A1L3MBTL1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117225188-A Preparation method of organic solvent nanofiltration membrane of rigid-flexible dual-network type IPN 浙江大学 2023-12-15 CN claimed
CN-117050393-A High-elastic wear-resistant rubber backing plate and preparation method thereof 台州大华铁路材料有限公司 2023-11-14 CN claimed
US-20220009899-A1 PROCESS AND COMPOUNDS FOR PREPARATION OF CANNABINOIDS EMBIO LIMITED (IN) 2022-01-13 US claimed
WO-2020099942-A1 PROCESS AND COMPOUNDS FOR PREPARATION OF CANNABINOIDS EMBIO LIMITED (IN) 2020-05-22 WO claimed
CN-1962614-A Felbinac acetaminopher ester and its preparation method GUANGDONG ZONK DRUG R & D LTD (CN) 2007-05-16 CN claimed
CN-120829567-B Tackifier for temperature-resistant fracturing fluid and preparation method 盘锦汇明实业有限公司 2025-12-02 CN disclosed
CN-120829567-A Tackifier for temperature-resistant fracturing fluid and preparation method 盘锦汇明实业有限公司 2025-10-24 CN disclosed
CN-117658373-A Waste salt recycling treatment method and system 杭州水处理技术研究开发中心有限公司 2024-03-08 CN disclosed
CN-117225188-A Preparation method of organic solvent nanofiltration membrane of rigid-flexible dual-network type IPN 浙江大学 2023-12-15 CN disclosed
CN-117050393-A High-elastic wear-resistant rubber backing plate and preparation method thereof 台州大华铁路材料有限公司 2023-11-14 CN disclosed
CN-113736252-A Composite material of phosphorus-containing polyamide modified montmorillonite modified nylon and preparation method thereof 深圳市集佳纸品包装有限公司 2021-12-03 CN disclosed
EP-2807171-B1 HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE NOVARTIS AG (CH) 2020-08-12 EP disclosed
US-4276078-A HALOGENATED AMIDE ANTIDOTES FOR THIOCARBAMYL HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1981-06-30 US disclosed
US-4269618-A COMPRISING A THIOLCARBAMATE AND AN ANTIDOTE OF A HALOALKYLAMIDO COMPOUND; COATING CROP SEEDS; APPLYING TO THE SOIL STAUFFER CHEMICAL COMPANY (US) 1981-05-26 US disclosed
US-4192883-A ANTITUSSIVES PIERRE FABRE, S.A. (FR) 1980-03-11 US disclosed
US-4180670-A Amino pyridine derivatives JOHN WYETH & BROTHER LIMITED (GB) 1979-12-25 US disclosed
US-4137070-A CONTAINING HERBICIDAL ANTIDOTE STAUFFER CHEMICAL COMPANY (US) 1979-01-30 US disclosed
US-4124376-A HALOACETANILIDE HERBICIDE AND HALO-N,N-BISALKENYLAMIDE NONPHYTOTOXIC ANTIDOTE STAUFFER CHEMICAL COMPANY (US) 1978-11-07 US disclosed
US-4122199-A Amides of pyrrolidinoethylamine which can be used in treatment of coughs PIERRE FABRE S.A. (FR) 1978-10-24 US disclosed
US-4021224-A THIOCARBAMATE, WEED PEST CONTROL, ANTIDOTES STAUFFER CHEMICAL COMPANY (US) 1977-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009899-A1 PROCESS AND COMPOUNDS FOR PREPARATION OF CANNABINOIDS CNR2, CNR1, DEGS1 SMN1; SMN2 3804/4885MAPT 2292/4885ALDH1A1 2097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.