SCHEMBL29015376

SCHEMBL29015376

N[C@@H](CC[C@@H]1CCCNC1=O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGER Q15109 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
GRM2 Q14416 4/20 0.34
GRM5 P41594 2/20 0.34
GRM6 O15303 2/20 0.34
GRM8 O00222 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GSR P00390 1/20 0.34
CYP1A2 P05177 1/20 0.34
GRIK1 P39086 1/20 0.34
GRIA1 P42261 1/20 0.34
GRIA2 P42262 1/20 0.34
GRIA3 P42263 1/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
GRIA4 P48058 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29015437 0.91 AGER (0.39) AGERGRM2GRM5GRM6GRM8
SCHEMBL27977572 0.91 AGER (0.39) AGERGRM2GRM5GRM6GRM8
SCHEMBL5964133 0.84 IDO1 (0.38) L3MBTL1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL26601402 0.84 IDO1 (0.38) L3MBTL1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL23824703 0.84 IDO1 (0.38) L3MBTL1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL26601378 0.83 IDO1 (0.38) L3MBTL1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL24190360 0.83 L3MBTL1 (0.36) L3MBTL1CCR2
SCHEMBL11269081 0.80 GRIN2D (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11280209 0.79 CCR2 (0.40) GRIN2DGRIN3BGRIK1GRIN1GRIN2A
SCHEMBL30397093 0.79 L3MBTL1 (0.36) L3MBTL1CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116685576-A Cysteine protease inhibitors and methods of use thereof 美商帕迪斯生物科学公司 2023-09-01 CN disclosed
CN-116096714-A Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections 安力高医药股份有限公司 2023-05-09 CN disclosed