Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29015396 | 0.87 | HTT (0.45) | HTTALDH1A1HPGDLMNAGAA | |
| SCHEMBL23709914 | 0.79 | LMNA (0.47) | HTTALDH1A1HPGDLMNAGAA | |
| SCHEMBL29015530 | 0.78 | KMO (0.39) | LMNA | |
| SCHEMBL23709923 | 0.78 | HTT (0.48) | HTTALDH1A1HPGDLMNAGAA | |
| SCHEMBL20536464 | 0.77 | RHEB (0.32) | ALDH1A1HPGD | |
| SCHEMBL20536463 | 0.77 | RHEB (0.32) | ALDH1A1HPGD | |
| SCHEMBL19330849 | 0.77 | TRPA1 (0.40) | ALDH1A1HPGDLMNAKMT2AL3MBTL1 | |
| SCHEMBL19330846 | 0.77 | TRPA1 (0.40) | ALDH1A1HPGDLMNAKMT2AL3MBTL1 | |
| SCHEMBL23709928 | 0.75 | LMNA (0.51) | HTTLMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL29062787 | 0.75 | KDM4E (0.39) | HTTHPGDLMNAKMT2ATLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |