Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 4/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034624 | 0.83 | NCF1 (0.52) | NCF1HSD17B10ALDH1A1HPGDKDM4E | |
| Trifluoroacetic Acid SCHEMBL30467710 | 0.75 | PLG (0.55) | C1SALDH1A1KDM4EL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL29015415 | 0.74 | C1S (0.62) | C1SALDH1A1KDM4ECYP1A2KMT2A | |
| SCHEMBL4284692 | 0.74 | ALDH1A1 (0.50) | NCF1HSD17B10ALDH1A1HPGDKDM4E | |
| Trifluoroacetic Acid SCHEMBL2723371 | 0.73 | HSP90AB1 (0.55) | KDM4EGAACYP1A2CYP2C19HTT | |
| SCHEMBL29949484 | 0.72 | ALDH1A1 (0.46) | NCF1HSD17B10ALDH1A1HPGDKDM4E | |
| Naphthalene SCHEMBL28279265 | 0.72 | CES1 (0.48) | HSD17B10ALDH1A1KDM4ECYP1A2KMT2A | |
| Trifluoroacetic Acid SCHEMBL29015449 | 0.72 | KDM4E (0.48) | C1SHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL27844899 | 0.72 | ALDH1A1 (0.44) | NCF1HSD17B10ALDH1A1HPGDKDM4E | |
| Phenanthrene SCHEMBL1839925 | 0.70 | HSD17B10 (0.55) | HSD17B10ALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |