Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653260 | 0.74 | PDE5A (0.41) | PDE5AKDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL8326659 | 0.72 | KDM4E (0.45) | PDE5AKDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL5567865 | 0.69 | PDE5A (0.39) | PDE5AGAAMAPT | |
| SCHEMBL5568857 | 0.69 | PDE5A (0.43) | PDE5AKDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL22697206 | 0.69 | GAA (0.39) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL5568366 | 0.69 | KDM4E (0.42) | PDE5AKDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL5917429 | 0.67 | PDE5A (0.44) | PDE5AGAAMAPT | |
| SCHEMBL16879027 | 0.65 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL16879026 | 0.65 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1CYP1A2GAA | |
| SCHEMBL8787725 | 0.64 | PDE5A (0.38) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |