Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843251 | 0.82 | MTNR1A (0.43) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL27768922 | 0.81 | GAA (0.56) | GAAMAPTPTPN7 | |
| SCHEMBL3195544 | 0.80 | KDM4E (0.49) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5568366 | 0.77 | KDM4E (0.42) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL926891 | 0.75 | GAA (0.65) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3989086 | 0.75 | GAA (0.65) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29569853 | 0.75 | GAA (0.65) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL644461 | 0.75 | GAA (0.65) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL926973 | 0.74 | GAA (0.63) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| Methyl Alcohol SCHEMBL28795455 | 0.74 | GAA (0.63) | GAAMAPTKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257388-A1 | GRANZYME B DIRECTED IMAGING AND THERAPY | CYTOSITE BIOPHARMA INC. (US) | 2023-08-17 | — | — | US | disclosed |
| US-11667645-B2 | Granzyme B directed imaging and therapy | CYTOSITE BIOPHARMA INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667645-B2 | Granzyme B directed imaging and therapy | CYTOSITE BIOPHARMA INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20230132386-A9 | GRANZYME B DIRECTED IMAGING AND THERAPY | CYTOSITE BIOPHARMA INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230132386-A9 | GRANZYME B DIRECTED IMAGING AND THERAPY | CYTOSITE BIOPHARMA INC. | 2023-04-27 | — | — | US | disclosed |
| US-20220135593-A1 | GRANZYME B DIRECTED IMAGING AND THERAPY | CYTOSITE BIOPHARMA INC (US) | 2022-05-05 | — | — | US | disclosed |
| US-20200369673-A1 | GRANZYME B DIRECTED IMAGING AND THERAPY | CYTOSITE BIOPHARMA INC. | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257388-A1 | GRANZYME B DIRECTED IMAGING AND THERAPY | GZMB, PRF1, CTSB | GAA 64/4885MAPT 4766/4885KDM4E 4784/4885 |
| US-20230132386-A9 | GRANZYME B DIRECTED IMAGING AND THERAPY | GZMB, PRF1, CTSB | GAA 68/4885MAPT 4577/4885KDM4E 4797/4885 |
| US-20220135593-A1 | GRANZYME B DIRECTED IMAGING AND THERAPY | GZMB, PRF1, CTSB | GAA 68/4885MAPT 4577/4885KDM4E 4797/4885 |
| US-20200369673-A1 | GRANZYME B DIRECTED IMAGING AND THERAPY | GZMB, PRF1, CTSB | GAA 64/4885MAPT 4766/4885KDM4E 4784/4885 |
| US-11667645-B2 | Granzyme B directed imaging and therapy | GZMB, PRF1, CTSB | GAA 64/4885MAPT 4766/4885KDM4E 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.