P-Xylene

P-Xylene

SCHEMBL3688331

COCCO.Cc1ccc(C)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
ACHE P22303 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 4/20 0.39
LMNA P02545 2/20 0.39
MMP13 P45452 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
NPC1 O15118 3/20 0.39
ALOX12 P18054 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 1/20 0.38
TSHR P16473 2/20 0.37
KMT2A Q03164 1/20 0.36
CYP3A4 P08684 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL8994094 0.97 GAA (0.41) GAAACHETDP1ALDH1A1LMNA
Toluene SCHEMBL306002 0.88 TSHR (0.50) GAAACHETDP1ALDH1A1LMNA
P-Xylene SCHEMBL235090 0.83 ACHE (0.53) ACHETDP1ALDH1A1LMNAHPGD
2-Methoxyethanol SCHEMBL15902281 0.82 ALDH1A1 (0.47) GAATDP1ALDH1A1LMNAMMP13
P-Xylene SCHEMBL27968200 0.81 TSHR (0.56) GAAACHETDP1ALDH1A1LMNA
P-Xylene SCHEMBL18334385 0.81 TSHR (0.56) GAAACHETDP1ALDH1A1LMNA
2-Methoxyethanol SCHEMBL9985959 0.81 ALDH1A1 (0.46) GAATDP1ALDH1A1LMNAMMP13
P-Xylene SCHEMBL235089 0.80 ACHE (0.50) GAAACHETDP1ALDH1A1LMNA
O-Xylene SCHEMBL16163023 0.80 TSHR (0.48) GAAACHEALDH1A1HPGDL3MBTL1
2-Methoxyethanol SCHEMBL1317307 0.80 TSHR (0.47) GAAALDH1A1HTTTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406363-B Method for producing (meth) acrylic ester 东亚合成株式会社 2021-10-08 CN disclosed
EP-3281933-B1 (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO LTD (JP) 2020-08-19 EP disclosed
CN-110014720-A Ink film, which is formed, uses master, pattern forming method, pattern film forming method and pattern membrane formation device 柯尼卡美能达株式会社 2019-07-16 CN disclosed
US-10266476-B2 (Meth)acrylate manufacturing method TOAGOSEI CO., LTD. (JP) 2019-04-23 US disclosed
US-10065916-B2 Method for producing (meth)acrylate TOAGOSEI CO., LTD (JP) 2018-09-04 US disclosed
US-20180118658-A1 (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO., LTD. (JP) 2018-05-03 US disclosed
US-20180105483-A1 METHOD FOR PRODUCING (METH)ACRYLATE TOAGOSEI CO., LTD. (JP) 2018-04-19 US disclosed
EP-3281933-A1 (METH)ACRYLATE MANUFACTURING METHOD Toagosei Co., Ltd. (JP) 2018-02-14 EP disclosed
EP-3269700-A1 METHOD FOR PRODUCING (METH)ACRYLATE Toagosei Co., Ltd. (JP) 2018-01-17 EP disclosed
US-9340701-B2 Curing agent for epoxy resin coatings SIKA TECHNOLOGY AG (CH) 2016-05-17 US disclosed
US-20100308718-A1 ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-12-09 US disclosed
US-7763761-B2 Asymmetric pyrene derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2010-07-27 US disclosed
EP-1661877-B1 PROCESS FOR PRODUCING AROMATIC ALDEHYDE IHARA CHEMICAL IND CO (JP) 2009-05-13 EP disclosed
US-7342138-B2 Process for producing aromatic aldehyde IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2008-03-11 US disclosed
EP-1749809-A1 ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-02-07 EP disclosed
US-20070004934-A1 Process for producing aromatic aldehyde IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2007-01-04 US disclosed
US-20060154107-A1 Asymmetric pyrene derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2006-07-13 US disclosed
EP-1661877-A1 PROCESS FOR PRODUCING AROMATIC ALDEHYDE Ihara Chemical Industry Co., Ltd. (JP) 2006-05-31 EP disclosed
US-6018013-A CONSISTS OF A POLYESTER OF GIVEN FORMULA DERIVED FROM 1,4-CYCLOHEXANEDICARBOXYLIC ACID AND A DIOL; A POLYOL; AND CURING AGENT; WORKABILITY AND HARDNESS NKK CORPORATION (JP) 2000-01-25 US disclosed
US-5817731-A POLYESTERDIOL NKK CORPORATION (JP) 1998-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100308718-A1 ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME ESR1, EBPL, JUP GAA 4085/4885ACHE 147/4885TDP1 577/4885
US-20180118658-A1 (METH)ACRYLATE MANUFACTURING METHOD MMAB, PAM, MAT2B GAA 1673/4885ACHE 1155/4885TDP1 2726/4885
US-10065916-B2 Method for producing (meth)acrylate MMAB, ADH5, ADH1A GAA 3049/4885ACHE 1384/4885TDP1 1846/4885
US-20180105483-A1 METHOD FOR PRODUCING (METH)ACRYLATE MMAB, ADH5, ADH1A GAA 3049/4885ACHE 1384/4885TDP1 1846/4885
US-20070004934-A1 Process for producing aromatic aldehyde ALKBH3, AOX1, ALDH3A1 GAA 969/4885ACHE 2211/4885TDP1 2816/4885
US-10266476-B2 (Meth)acrylate manufacturing method MMAB, PAM, MAT2B GAA 1673/4885ACHE 1155/4885TDP1 2726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.