Toluene

Toluene

SCHEMBL306002

COCCO.Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
LMNA P02545 2/20 0.50
ALOX12 P18054 1/20 0.50
ACHE P22303 1/20 0.50
ALDH1A1 P00352 1/20 0.46
RECQL P46063 1/20 0.46
CA2 P00918 1/20 0.38
POLB P06746 1/20 0.37
HPGD P15428 2/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
ADRB2 P07550 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CHRM3 P20309 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL926846 0.90 TSHR (0.41) TSHRLMNAALOX12ACHEALDH1A1
P-Xylene SCHEMBL3688331 0.88 GAA (0.43) TSHRLMNAALOX12ACHEALDH1A1
Toluene SCHEMBL28107709 0.88 MEN1 (0.42) TSHRLMNAALOX12ACHEALDH1A1
Toluene SCHEMBL5067632 0.87 LMNA (0.46) TSHRLMNAALOX12ACHEALDH1A1
P-Xylene SCHEMBL8994094 0.86 GAA (0.41) TSHRLMNAALOX12ACHEALDH1A1
Toluene SCHEMBL4761329 0.85 TSHR (0.61) TSHRLMNAALOX12ACHECA2
Toluene SCHEMBL28194370 0.85 LMNA (0.44) TSHRLMNAALOX12ACHEALDH1A1
M-Xylene SCHEMBL29016502 0.84 ACHE (0.52) LMNAACHEALDH1A1POLBNPC1
Toluene SCHEMBL4915685 0.84 LMNA (0.48) TSHRLMNAALOX12ACHEALDH1A1
O-Xylene SCHEMBL16163023 0.84 TSHR (0.48) TSHRACHEALDH1A1RECQLCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368123-B Substituted imidazolyl compound and pharmaceutical composition thereof 深圳市塔吉瑞生物医药有限公司 2021-02-19 CN disclosed
CN-108368123-A A kind of substituted imidazole-based compounds and its pharmaceutical composition 深圳市塔吉瑞生物医药有限公司 2018-08-03 CN disclosed
CN-104592506-B N-methoxypolyethylene glycols-N,-carbamyl maleimide and preparation method thereof 沈阳工业大学 2017-01-18 CN disclosed
CN-104749885-A Photosensitive resin composition, photosensitive element, mask material for sandblasting and surface-processing method for workpiece HITACHI CHEMICAL CO LTD 2015-07-01 CN disclosed
CN-104592506-A N-methoxypolyethylene glycols-N,-carbamyl maleimide and preparation method thereof UNIV SHENYANG TECHNOLOGY 2015-05-06 CN disclosed
CN-102351801-B One-pot preparation method of sintofen SHANGHAI HETENG FINE CHEMICAL CO LTD 2014-02-05 CN disclosed
CN-102360163-B Photosensitive element HITACHI CHEMICAL CO LTD 2013-06-12 CN disclosed
CN-102707571-A Photosensitive element HITACHI CHEMICAL CO LTD 2012-10-03 CN disclosed
CN-101563651-B Photosensitive element HITACHI CHEMICAL CO LTD 2012-07-04 CN disclosed
CN-102360163-A Photosensitive element HITACHI CHEMICAL CO LTD 2012-02-22 CN disclosed
US-6264866-B1 CASTING ORGANIC SOLVENT SOLUTION OF POLYAMIDE ACID AND CURING AGENT SELECTED FROM DEHYDRATING AGENT AND TERTIARY AMINE INTO FILM SHAPE; HEATING TO FORM PREFILM; HEATING PREFILM TO OBTAIN AN ADHESIVE POLYIMIDE FILM KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-07-24 US disclosed
EP-0528260-B1 Multi-usable thermal transfer ink sheet FUJI KAGAKU SHIKOGYO (JP) 1997-04-23 EP disclosed
US-5326620-A Multilayer heat exchangers with ethylene copolymers and color, overcoatings FUJICOPIAN CO., LTD. (JP) 1994-07-05 US disclosed
EP-0528260-A1 Multi-usable thermal transfer ink sheet FUJICOPIAN CO., LTD. (JP) 1993-02-24 EP disclosed
EP-0104627-B1 AN IMAGE RECEPTOR AND METHOD FOR PRODUCING AN OPAQUE PRINT THEREON Coulter Systems Corporation (US) 1987-12-09 EP disclosed
US-4510225-A EMBEDDING TONER PARTICLES IN A SUBSTRATELAMINATED SOFTENED THERMOPLASTIC RESIN COULTER SYSTEMS CORPORATION (US) 1985-04-09 US disclosed
EP-0104627-A1 An image receptor and method for producing an opaque print thereon Coulter Systems Corporation (US) 1984-04-04 EP disclosed
US-4434259-A MODIFIED POLYVINYL ACETATE AND CELLULOSE NITRATE NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1984-02-28 US disclosed
US-4122223-A ARTIFICIAL LEATHER INMONT CORPORATION (US) 1978-10-24 US disclosed
US-3957918-A VINYL POLYMER FORD MOTOR COMPANY (US) 1976-05-18 US disclosed