Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319061 | 0.86 | SMN1; SMN2 (0.72) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL2901749 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL27913467 | 0.86 | MEN1 (0.89) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL1959291 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL12431397 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL13301476 | 0.84 | L3MBTL1 (0.72) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL13301466 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL31512479 | 0.82 | L3MBTL1 (0.60) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL12792825 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL12387048 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2KMT2AMEN1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494642-B1 | Organosilicon derivatives of aminohydroxybenzophenones and their use as UV-A filters in cosmetic preparations | DSM IP ASSETS BV (NL) | 2010-03-10 | — | — | EP | disclosed |
| CN-100424076-C | Organosiloxane derivatives of aminohydroxybenzophenones and their use as UV-A filters in cosmetic preparations | DSM IP ASSETS BV (NL) | 2008-10-08 | — | — | CN | disclosed |
| US-7388102-B2 | Organosilicone derivatives of amino hydroxybenzophenones and their use as UV-A filters in cosmetic preparations | DSM IP ASSETS B.V. (NL) | 2008-06-17 | — | — | US | disclosed |
| US-20050255066-A1 | Organosilicone derivatives of amino hydroxybenzophenones and their use as uv-a filters in cosmetic preparations | DSM NUTRITIONAL PRODUCTS LTD F/K/A ROCHE VITAMINS AG (CH) | 2005-11-17 | — | — | US | disclosed |
| CN-1646091-A | Organosilicone derivatives of amino hydroxybenzophenones and their use as UV-A filters in cosmetic preparations | DSM IP ASSETS BV (NL) | 2005-07-27 | — | — | CN | disclosed |
| EP-1494642-A1 | ORGANOSILICONE DERIVATIVES OF AMINO HYDROXYBENZOPHENONES AND THEIR USE AS UV-A FILTERS IN COSMETIC PREPARATIONS | DSM IP Assets B.V. (NL) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003086340-A1 | ORGANOSILICONE DERIVATIVES OF AMINO HYDROXYBENZOPHENONES AND THEIR USE AS UV-A FILTERS IN COSMETIC PREPARATIONS | DSM IP ASSETS B.V. (NL) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255066-A1 | Organosilicone derivatives of amino hydroxybenzophenones and their use as uv-a filters in cosmetic preparations | CUTA, TYR, ERCC5 | SMN1; SMN2 4864/4885KMT2A 2186/4885MEN1 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.