SCHEMBL2901749

SCHEMBL2901749

C=CCOC(=O)c1ccccc1C(=O)c1ccc(N(CC)CC)cc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 4/20 0.65
▸ MEN1 O00255 2/20 0.65
▸ KMT2A Q03164 2/20 0.65
▸ L3MBTL1 Q9Y468 2/20 0.65
▸ CYP3A4 P08684 2/20 0.55
▸ ALDH1A1 P00352 7/20 0.51
▸ KDM4E B2RXH2 5/20 0.51
▸ GAA P10253 4/20 0.51
▸ POLB P06746 1/20 0.51
▸ TSHR P16473 2/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ MAPT P10636 7/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ LMNA P02545 3/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ NFKB2 Q00653 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13301466 0.91 SMN1; SMN2 (0.67) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4
SCHEMBL6441612 0.90 CYP3A4 (0.56) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4
SCHEMBL31512479 0.87 L3MBTL1 (0.60) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4
SCHEMBL13301476 0.87 L3MBTL1 (0.72) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4
SCHEMBL12431397 0.87 SMN1; SMN2 (0.72) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4
SCHEMBL2901653 0.86 SMN1; SMN2 (0.67) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4
SCHEMBL13301485 0.85 L3MBTL1 (0.69) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4
SCHEMBL13301464 0.85 L3MBTL1 (0.69) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4
SCHEMBL2319061 0.84 SMN1; SMN2 (0.72) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4
SCHEMBL27913467 0.84 MEN1 (0.89) SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765967-B2 Microcapsules with UV filter activity and process for producing them DSM IP ASSETS B.V. (NE) 2014-07-01 — — US disclosed
US-8765967-B2 Microcapsules with UV filter activity and process for producing them DSM IP ASSETS B.V. (NE) 2014-07-01 — — US disclosed
EP-1722863-B1 MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM DSM IP ASSETS BV (NL) 2012-02-08 — — EP disclosed
US-20120022265-A1 MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM BERG-SCHULTZ KATJA (CH) 2012-01-26 — — US disclosed
US-20120022265-A1 MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM BERG-SCHULTZ KATJA (CH) 2012-01-26 — — US disclosed
EP-1861465-B1 CHROMOPHORE COATED METAL OXIDE PARTICLES DSM IP ASSETS BV (NL) 2010-10-13 — — EP disclosed
EP-1494642-B1 Organosilicon derivatives of aminohydroxybenzophenones and their use as UV-A filters in cosmetic preparations DSM IP ASSETS BV (NL) 2010-03-10 — — EP disclosed
US-20090291107-A1 Chromophore Coated Metal Oxide Particles DSM IP ASSETS B.V. (NL) 2009-11-26 — — US disclosed
US-20090291107-A1 Chromophore Coated Metal Oxide Particles DSM IP ASSETS B.V. (NL) 2009-11-26 — — US disclosed
CN-100424076-C Organosiloxane derivatives of aminohydroxybenzophenones and their use as UV-A filters in cosmetic preparations DSM IP ASSETS BV (NL) 2008-10-08 — — CN disclosed
US-7388102-B2 Organosilicone derivatives of amino hydroxybenzophenones and their use as UV-A filters in cosmetic preparations DSM IP ASSETS B.V. (NL) 2008-06-17 — — US disclosed
US-20070190325-A1 Microcapsules with uv filter activity and process for producing them DSM IP ASSETS B.V. (NL) 2007-08-16 — — US disclosed
US-20070190325-A1 Microcapsules with uv filter activity and process for producing them DSM IP ASSETS B.V. (NL) 2007-08-16 — — US disclosed
US-20050255066-A1 Organosilicone derivatives of amino hydroxybenzophenones and their use as uv-a filters in cosmetic preparations DSM NUTRITIONAL PRODUCTS LTD F/K/A ROCHE VITAMINS AG (CH) 2005-11-17 — — US disclosed
CN-1646091-A Organosilicone derivatives of amino hydroxybenzophenones and their use as UV-A filters in cosmetic preparations DSM IP ASSETS BV (NL) 2005-07-27 — — CN disclosed
EP-1494642-A1 ORGANOSILICONE DERIVATIVES OF AMINO HYDROXYBENZOPHENONES AND THEIR USE AS UV-A FILTERS IN COSMETIC PREPARATIONS DSM IP Assets B.V. (NL) 2005-01-12 — — EP disclosed
WO-2003086340-A1 ORGANOSILICONE DERIVATIVES OF AMINO HYDROXYBENZOPHENONES AND THEIR USE AS UV-A FILTERS IN COSMETIC PREPARATIONS DSM IP ASSETS B.V. (NL) 2003-10-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090291107-A1 Chromophore Coated Metal Oxide Particles PPOX, MITF, MC1R SMN1; SMN2 4283/4885MEN1 538/4885KMT2A 2271/4885
US-20050255066-A1 Organosilicone derivatives of amino hydroxybenzophenones and their use as uv-a filters in cosmetic preparations CUTA, TYR, ERCC5 SMN1; SMN2 4864/4885MEN1 2105/4885KMT2A 2186/4885
US-20120022265-A1 MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM UACA, UROD, UMPS SMN1; SMN2 4461/4885MEN1 1079/4885KMT2A 4368/4885
US-20070190325-A1 Microcapsules with uv filter activity and process for producing them UACA, UROD, UMPS SMN1; SMN2 4461/4885MEN1 1079/4885KMT2A 4368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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