Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905905 | 0.80 | HSD11B1 (0.35) | HSD11B1S1PR3GAAPOLBGPR119 | |
| SCHEMBL2783257 | 0.70 | TSHR (0.48) | HSD11B1POLB | |
| SCHEMBL2901669 | 0.69 | CSNK1E (0.32) | POLB | |
| SCHEMBL27107435 | 0.66 | SIRT3 (0.37) | GAAPOLB | |
| SCHEMBL11867319 | 0.64 | TTR (0.39) | GAA | |
| SCHEMBL2901213 | 0.62 | HSD11B1 (0.40) | HSD11B1S1PR3GAAGPR119 | |
| SCHEMBL23600938 | 0.60 | CYP3A4 (0.50) | POLB | |
| SCHEMBL2381135 | 0.60 | CYP3A4 (0.41) | POLB | |
| SCHEMBL2781610 | 0.60 | TSHR (0.49) | HSD11B1 | |
| SCHEMBL9812889 | 0.60 | S1PR3 (0.53) | HSD11B1S1PR3GAAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871760-B1 | CYANO ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-08-11 | — | — | EP | disclosed |
| US-7601743-B2 | Cyano anthranilamide insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| EP-1871760-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | Syngeta Participations AG (CH) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006111341-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | CRY1, CRYAA, ALDH7A1 | HSD11B1 1171/4885S1PR3 4762/4885GAA 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.