SCHEMBL2901669

SCHEMBL2901669

Cc1cc(I)cc(C(=O)NC2(C3CC3)CC2)c1C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.32
TAS1R3 Q7RTX0 2/20 0.30
TAS1R1 Q7RTX1 2/20 0.30
TAS1R2 Q8TE23 2/20 0.30
P2RX7 Q99572 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2901675 0.85 KDM4E (0.33) P2RX7
SCHEMBL2905901 0.82 CXCR5 (0.34) CSNK1E
SCHEMBL13208800 0.72 CRBN (0.38) P2RX7
SCHEMBL2901672 0.69 HSD11B1 (0.35) POLB
SCHEMBL2901211 0.67 CXCR5 (0.35)
SCHEMBL27107435 0.61 SIRT3 (0.37) POLB
SCHEMBL2900855 0.61 POLB (0.36) POLB
SCHEMBL11867319 0.60 TTR (0.39)
SCHEMBL2899813 0.60 F9 (0.35) POLB
SCHEMBL10280535 0.60 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1871760-B1 CYANO ANTHRANILAMIDE INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-08-11 EP disclosed
US-7601743-B2 Cyano anthranilamide insecticides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-13 US disclosed
US-20080182750-A1 Cyano Anthranilamide Insecticides SYNGENTA CROP PROTECTION, INC. (US) 2008-07-31 US disclosed
EP-1871760-A1 CYANO ANTHRANILAMIDE INSECTICIDES Syngeta Participations AG (CH) 2008-01-02 EP disclosed
WO-2006111341-A1 CYANO ANTHRANILAMIDE INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2006-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182750-A1 Cyano Anthranilamide Insecticides CRY1, CRYAA, ALDH7A1 CSNK1E 752/4885TAS1R3 1259/4885TAS1R1 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.