Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10630490 | 0.81 | CYP2C9 (0.44) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL10792715 | 0.80 | CYP2C9 (0.43) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL10791376 | 0.75 | TSHR (0.42) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL30839559 | 0.74 | TSHR (0.41) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL9518408 | 0.73 | TSHR (0.40) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL2437697 | 0.70 | HTR6 (0.43) | CYP2C19ALDH1A1KDM4ETAAR1ADCY10 | |
| SCHEMBL9953712 | 0.69 | L3MBTL1 (0.50) | HRH4HRH3TDP1ALDH1A1TAAR1 | |
| SCHEMBL16598137 | 0.69 | CYP2C9 (0.40) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL11048352 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KDM4ETAAR1ADCY10HTR2C | |
| SCHEMBL10792525 | 0.69 | CYP2C9 (0.46) | CYP2C9TSHRCYP2C19MTORHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105939-A | Fused bicyclic sGC stimulators | 帝善多制药公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-109790167-B | SGC stimulators | 塞科里昂医疗股份有限公司 | 2023-06-20 | — | — | CN | disclosed |