Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 4/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | CHUK | O15111 | 2/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960140 | 0.73 | PI4K2A (0.46) | PI4K2AIKBKBCHUKALDH1A1PDPK1 | |
| SCHEMBL20476405 | 0.72 | KDM5C (0.51) | HDAC6GRM4MAPK1MAOBRIPK1 | |
| SCHEMBL1207795 | 0.71 | HDAC6 (0.48) | HDAC6PI4K2ASYKIKBKBCHUK | |
| SCHEMBL31707849 | 0.71 | LIMK1 (0.43) | HDAC6PI4K2ASYKGRM4MAOB | |
| Hydrochloric Acid SCHEMBL3831639 | 0.70 | HDAC6 (0.47) | HDAC6PI4K2ASYKIKBKBCHUK | |
| SCHEMBL7159839 | 0.69 | MAPT (0.44) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL2564058 | 0.66 | ROCK2 (0.50) | MEN1ALDH1A1MAPTKMT2ACHEK1 | |
| SCHEMBL30039613 | 0.66 | CSNK1A1 (0.49) | HDAC6PI4K2ASYKIKBKBCHUK | |
| SCHEMBL21359258 | 0.65 | HDAC6 (0.66) | HDAC6SYKMAPTMAPK1MAOB | |
| SCHEMBL21358965 | 0.65 | HDAC6 (0.45) | HDAC6PI4K2AALDH1A1MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635954-A1 | INDUCER FOR INDUCING MESENCHYMAL-EPITHELIAL TRANSITION AND REPROGRAMMING | Iregene Therapeutics Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024124463-A1 | PYRROLOPYRIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 武汉睿健医药科技有限公司 | 2024-06-20 | — | — | WO | disclosed |
| WO-2024124464-A1 | INDUCER FOR INDUCING MESENCHYMAL-EPITHELIAL TRANSITION AND REPROGRAMMING | 武汉睿健医药科技有限公司 | 2024-06-20 | — | — | WO | disclosed |
| CN-116283964-A | Pyrrolopyridine derivative, and pharmaceutical composition and application thereof | 武汉睿健医药科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115948325-A | Inducer for inducing transformation and reprogramming of mesenchymal cells to epithelial cells | 武汉睿健医药科技有限公司 | 2023-04-11 | — | — | CN | disclosed |