Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamethazine SCHEMBL17256221 | 0.77 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2CYP3A4TDP1GAA | |
| Sulfamethazine SCHEMBL29918086 | 0.77 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2CYP3A4TDP1GAA | |
| Sulfamethazine SCHEMBL151305 | 0.77 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2CYP3A4TDP1GAA | |
| SCHEMBL356140 | 0.77 | MCL1 (0.58) | ALDH1A1SMN1; SMN2GAALMNATSHR | |
| Sulfamethazine SCHEMBL28567572 | 0.76 | ALDH1A1 (0.97) | ALDH1A1SMN1; SMN2CYP3A4TDP1GAA | |
| Sulfamethazine SCHEMBL1442165 | 0.76 | ALDH1A1 (0.97) | ALDH1A1SMN1; SMN2CYP3A4TDP1GAA | |
| Sulfamethazine SCHEMBL3495558 | 0.76 | ALDH1A1 (0.97) | ALDH1A1SMN1; SMN2CYP3A4TDP1GAA | |
| SCHEMBL3644476 | 0.75 | TSHR (0.62) | ALDH1A1SMN1; SMN2CYP3A4TDP1GAA | |
| Sulfamethazine SCHEMBL28028309 | 0.75 | ALDH1A1 (0.94) | ALDH1A1SMN1; SMN2CYP3A4TDP1GAA | |
| Sulfamethazine SCHEMBL11708760 | 0.74 | ALDH1A1 (0.91) | ALDH1A1SMN1; SMN2CYP3A4TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063236-A | Production process for removing impurities from sulfadimidine | 佛山市南海北沙制药有限公司 | 2023-05-05 | — | — | CN | disclosed |