Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 17/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229227 | 0.71 | HPGDS (0.33) | — | |
| SCHEMBL12906161 | 0.68 | NOTUM (0.59) | NOTUMKDM4ELMNATSHR | |
| SCHEMBL6911489 | 0.63 | GRM5 (0.33) | — | |
| SCHEMBL17694561 | 0.60 | NOTUM (0.78) | NOTUMKDM4ELMNATSHR | |
| SCHEMBL25219682 | 0.60 | — | — | |
| SCHEMBL28394924 | 0.60 | NOTUM (0.50) | NOTUMKDM4ETSHR | |
| SCHEMBL6909709 | 0.59 | NISCH (0.46) | KDM4ELMNATSHR | |
| SCHEMBL17044070 | 0.59 | NOTUM (0.44) | NOTUM | |
| SCHEMBL2670934 | 0.58 | NOTUM (0.65) | NOTUMKDM4ELMNATSHR | |
| SCHEMBL1171231 | 0.58 | NISCH (0.38) | KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769420-A | Combination therapy for treating cancer using PRMT5 inhibitors | 米拉蒂医疗股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117769421-A | Combination therapy for treating cancer using PRMT5 inhibitors | 米拉蒂医疗股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-111836680-B | Multifunctional porous material for water purification and treatment | 南佛罗里达大学 | 2023-06-20 | — | — | CN | disclosed |