Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17925880 | 0.74 | FABP6 (0.34) | HPGDSADRA1DADRA1AADRA1B | |
| SCHEMBL29019362 | 0.71 | NOTUM (0.38) | — | |
| SCHEMBL17468569 | 0.70 | HPGDS (0.37) | HPGDSADRA1DADRA1AADRA1BLTA4H | |
| SCHEMBL100765 | 0.69 | HPGDS (0.46) | HPGDSADRA1DADRA1AADRA1BLTA4H | |
| SCHEMBL6911489 | 0.68 | GRM5 (0.33) | ADRA1DADRA1AADRA1BGRM5 | |
| SCHEMBL17982505 | 0.68 | MMP12 (0.33) | HPGDSADRA1DADRA1AADRA1BLTA4H | |
| SCHEMBL6909709 | 0.64 | NISCH (0.46) | ADRA1DADRA1AADRA1B | |
| SCHEMBL1920363 | 0.64 | LTA4H (0.36) | HPGDSADRA1DADRA1AADRA1BLTA4H | |
| SCHEMBL7367387 | 0.63 | CHRM1 (0.33) | — | |
| SCHEMBL28596689 | 0.63 | NISCH (0.46) | ADRA1DADRA1AADRA1BGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100586945-C | Substituted 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazine derivatives and their use as neurokinin antagonists | JANSSEN PHARMACEUTICA NV | 2010-02-03 | — | — | CN | claimed |
| CN-101090723-A | Piperazine urea derivatives for the treatment of endometriosis | SCHERING AG (DE) | 2007-12-19 | — | — | CN | claimed |
| CN-1726207-A | Substituted 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazine derivatives and their use as neurokinin antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2006-01-25 | — | — | CN | claimed |
| CN-1290250-A | Sulfonylamino derivatives which inhibit matrix-degrading metallopr teinases | NOVARTIS AG (CH) | 2001-04-04 | — | — | CN | claimed |
| CN-117377673-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-109195974-A | Isothiazolopyridinones, method for the production thereof and use thereof as herbicides and/or plant growth regulators | 拜耳作物科学股份公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-102143961-A | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON INC | 2011-08-03 | — | — | CN | disclosed |
| CN-101754963-A | spirocyclopropyl piperidine derivatives | ASTRAZENECA AB | 2010-06-23 | — | — | CN | disclosed |
| CN-100586945-C | Substituted 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazine derivatives and their use as neurokinin antagonists | JANSSEN PHARMACEUTICA NV | 2010-02-03 | — | — | CN | disclosed |
| CN-101534828-A | Allosteric modulators of the A1 adenosine receptor | KING PHARMACEUTICALS RES & DEV (US) | 2009-09-16 | — | — | CN | disclosed |
| CN-100384834-C | Epothilone derivatives | BRISTOL MYERS SQUIBB CO (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-101090723-A | Piperazine urea derivatives for the treatment of endometriosis | SCHERING AG (DE) | 2007-12-19 | — | — | CN | disclosed |
| CN-1290250-A | Sulfonylamino derivatives which inhibit matrix-degrading metallopr teinases | NOVARTIS AG (CH) | 2001-04-04 | — | — | CN | disclosed |
| CN-1262272-A | HIV proteinase inhibitor | AGOURON PHARMA (US) | 2000-08-09 | — | — | CN | disclosed |
| CN-1253548-A | HIV protease inhibitors | AGOURON PHARMA (US) | 2000-05-17 | — | — | CN | disclosed |
| CN-1252799-A | N-heterocyclic derivatives as NOS inhibitor | BERLEX LAB (US) | 2000-05-10 | — | — | CN | disclosed |
| CN-1046269-C | HIV protease inhibitors | AGOURON PHARMA (US) | 1999-11-10 | — | — | CN | disclosed |
| CN-1131942-A | HIV protease inhibitors | AGOURON PHARMACEUTICALS INS (US) | 1996-09-25 | — | — | CN | disclosed |
| CN-1097192-A | Retroviral protease inhibitors | AMERICAN CYANAMID CO (US) | 1995-01-11 | — | — | CN | disclosed |
| CN-1071917-A | Quinazoline derivant as human immunodeficiency virus reversed transcriptive enzyme antagonist | MERCK & CO INC (US) | 1993-05-12 | — | — | CN | disclosed |