Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | CTRC | Q99895 | 3/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29961695 | 1.00 | KMO (0.51) | KMOMCL1CTRCMAP4K4MKNK1 | |
| SCHEMBL29020201 | 0.85 | KMO (0.51) | KMOMCL1CTRCMAP4K4XDH | |
| SCHEMBL29961689 | 0.85 | KMO (0.51) | KMOMCL1CTRCMAP4K4XDH | |
| SCHEMBL21001267 | 0.83 | MCL1 (0.61) | KMOMCL1CTRCKDM4EMEN1 | |
| SCHEMBL29020197 | 0.82 | MCL1 (0.55) | KMOMCL1CTRCMAP4K4KDM4E | |
| SCHEMBL29961681 | 0.79 | KMO (0.56) | KMOMCL1CTRCMAP4K4KDM4E | |
| SCHEMBL29020139 | 0.79 | KMO (0.56) | KMOMCL1CTRCMAP4K4KDM4E | |
| SCHEMBL1535621 | 0.78 | CTRC (0.49) | KMOMCL1CTRCMAP4K4GABRA2 | |
| SCHEMBL29808904 | 0.75 | CTRC (0.55) | KMOMCL1CTRCMKNK1MKNK2 | |
| SCHEMBL28803081 | 0.75 | CTRC (0.55) | KMOMCL1CTRCMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093400-B | AhR inhibitor, application and preparation method thereof | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115093400-A | AhR inhibitor and application and preparation method thereof | 重庆华森制药股份有限公司 | 2022-09-23 | — | — | CN | disclosed |