Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 8/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | CTRC | Q99895 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29961689 | 1.00 | KMO (0.51) | KMOMCL1CTRCMAP4K4ADORA3 | |
| SCHEMBL29961695 | 0.85 | KMO (0.51) | KMOMCL1CTRCMAP4K4ADORA3 | |
| SCHEMBL29020124 | 0.85 | KMO (0.51) | KMOMCL1CTRCMAP4K4ADORA3 | |
| SCHEMBL21001267 | 0.83 | MCL1 (0.61) | KMOMCL1CTRCADORA3KDM4E | |
| SCHEMBL29020197 | 0.82 | MCL1 (0.55) | KMOMCL1CTRCMAP4K4ADORA3 | |
| SCHEMBL29062403 | 0.80 | KMO (0.59) | KMOMAP4K4KDM4E | |
| SCHEMBL29020139 | 0.79 | KMO (0.56) | KMOMCL1CTRCMAP4K4ADORA3 | |
| SCHEMBL29961681 | 0.79 | KMO (0.56) | KMOMCL1CTRCMAP4K4ADORA3 | |
| SCHEMBL29808904 | 0.75 | CTRC (0.55) | KMOMCL1CTRCDHODHMEN1 | |
| SCHEMBL3408569 | 0.74 | KMO (0.71) | KMOMCL1CTRCDHODHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093400-B | AhR inhibitor, application and preparation method thereof | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115093400-A | AhR inhibitor and application and preparation method thereof | 重庆华森制药股份有限公司 | 2022-09-23 | — | — | CN | disclosed |