Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 5/20 | 0.43 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29961598 | 1.00 | MAPK1 (0.49) | MAPK1PDPK1RPS6KB1LIPGCLK1 | |
| SCHEMBL29020122 | 1.00 | MAPK1 (0.49) | MAPK1PDPK1RPS6KB1LIPGCLK1 | |
| SCHEMBL29020217 | 0.93 | CLK1 (0.47) | MAPK1PDPK1RPS6KB1CLK1PDE2A | |
| SCHEMBL29020220 | 0.93 | CLK1 (0.47) | MAPK1PDPK1RPS6KB1CLK1PDE2A | |
| SCHEMBL29961633 | 0.93 | CLK1 (0.47) | MAPK1PDPK1RPS6KB1CLK1PDE2A | |
| SCHEMBL29020117 | 0.85 | KCNT1 (0.44) | MAPK1CLK1KCNT1ROCK2ROCK1 | |
| SCHEMBL29020149 | 0.82 | MAPK1 (0.44) | MAPK1CLK1PDE2AKCNT1ROCK2 | |
| SCHEMBL29020185 | 0.82 | ROCK2 (0.47) | MAPK1CLK1PFKFB3KCNT1ROCK2 | |
| SCHEMBL29020159 | 0.81 | CLK1 (0.50) | MAPK1CLK1PDE2APFKFB3 | |
| SCHEMBL29961667 | 0.81 | CLK1 (0.50) | MAPK1CLK1PDE2APFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093400-B | AhR inhibitor, application and preparation method thereof | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115093400-A | AhR inhibitor and application and preparation method thereof | 重庆华森制药股份有限公司 | 2022-09-23 | — | — | CN | disclosed |