Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 8/20 | 0.46 |
| ▸ | ABL1 | P00519 | 3/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | PRKACG | P22612 | 1/20 | 0.41 |
| ▸ | PRKACB | P22694 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29020227 | 0.90 | PDE2A (0.43) | PDE2AROCK2PRKG1CYP2C9PRKACA | |
| SCHEMBL29020149 | 0.89 | MAPK1 (0.44) | PDE2AROCK2PRKG1CYP2C9PRKACA | |
| SCHEMBL29020117 | 0.89 | KCNT1 (0.44) | ROCK2PRKG1CYP2C9PRKACAPRKACG | |
| SCHEMBL29020210 | 0.88 | CLK1 (0.48) | AHRROCK2PRKG1CYP2C9PRKACA | |
| SCHEMBL29020185 | 0.87 | ROCK2 (0.47) | ROCK2PRKG1CYP2C9PRKACAPRKACG | |
| SCHEMBL29020203 | 0.85 | PHGDH (0.41) | ROCK2PRKG1CYP2C9PRKACAPRKACG | |
| SCHEMBL21004853 | 0.82 | AHR (0.71) | AHRPDE2AABL1BTKADORA3 | |
| SCHEMBL21004852 | 0.82 | AHR (0.71) | AHRPDE2AABL1BTKADORA3 | |
| SCHEMBL21001691 | 0.82 | AHR (0.54) | AHRPDE2AABL1BTKADORA3 | |
| SCHEMBL21001690 | 0.82 | AHR (0.54) | AHRPDE2AABL1BTKADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093400-B | AhR inhibitor, application and preparation method thereof | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115093400-A | AhR inhibitor and application and preparation method thereof | 重庆华森制药股份有限公司 | 2022-09-23 | — | — | CN | disclosed |