Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.57 |
| ▸ | KMO | O15229 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | MARS1 | P56192 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21001335 | 0.99 | KMO (0.58) | DHODHKMOADORA3AKR1C2AKR1C1 | |
| Potassium SCHEMBL29961825 | 0.97 | DHODH (0.57) | DHODHKMOADORA3AKR1C2AKR1C1 | |
| Potassium Ion SCHEMBL29020198 | 0.86 | DHODH (0.50) | DHODHKMOADORA3AKR1C2AKR1C1 | |
| SCHEMBL24060792 | 0.85 | KMO (0.52) | DHODHKMOADORA3SCN10ASCN9A | |
| SCHEMBL21001359 | 0.85 | ADORA3 (0.61) | DHODHKMOADORA3AKR1C2AKR1C1 | |
| SCHEMBL29020161 | 0.82 | KMO (0.61) | KMOADORA3MARS1MCL1 | |
| SCHEMBL29062398 | 0.82 | KMO (0.68) | DHODHKMOADORA3SCN9AMCL1 | |
| SCHEMBL3408828 | 0.81 | KMO (0.62) | KMOADORA3MARS1MCL1 | |
| SCHEMBL29020155 | 0.80 | KMO (0.69) | DHODHKMOMCL1 | |
| Potassium SCHEMBL29961608 | 0.80 | KMO (0.61) | KMOADORA3MARS1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093400-B | AhR inhibitor, application and preparation method thereof | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115093400-A | AhR inhibitor and application and preparation method thereof | 重庆华森制药股份有限公司 | 2022-09-23 | — | — | CN | disclosed |