Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | PKLR | P30613 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906203 | 0.99 | TDP1 (0.40) | CA2PGAM1TDP1PKLRPTPN1 | |
| SCHEMBL13568736 | 0.99 | CA2 (0.39) | CA2PGAM1TDP1PKLRPTPN1 | |
| SCHEMBL2906201 | 0.90 | PGAM1 (0.41) | CA2PGAM1TDP1PKLRPTPN1 | |
| SCHEMBL2906943 | 0.86 | KDM4E (0.43) | PGAM1KDM4EALDH1A1MAPT | |
| SCHEMBL2904057 | 0.86 | KDM4E (0.43) | PGAM1KDM4EALDH1A1MAPT | |
| SCHEMBL2908408 | 0.80 | CA2 (0.39) | CA2PGAM1PKLRKDM4EALDH1A1 | |
| SCHEMBL2903786 | 0.76 | THRB (0.40) | PGAM1 | |
| SCHEMBL2903559 | 0.75 | CA2 (0.39) | CA2TDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL13568743 | 0.74 | PGAM1 (0.45) | PGAM1TDP1PKLRPTPN1KDM4E | |
| SCHEMBL2906255 | 0.74 | TDP1 (0.40) | CA2TDP1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9039946-B2 | Reversibly thermochromic compositions | BASF SE (DE) | 2015-05-26 | — | — | US | disclosed |
| EP-1888705-B1 | Reversibly thermochromic compositions | BASF SE (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-20090302284-A1 | Reversibly Thermochromic Compositions | CIBA CORPORATION | 2009-12-10 | — | — | US | disclosed |
| EP-1888705-A1 | REVERSIBLY THERMOCHROMIC COMPOSITIONS | Ciba Specialty Chemicals Holding, Inc. (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006131465-A1 | REVERSIBLY THERMOCHROMIC COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090302284-A1 | Reversibly Thermochromic Compositions | DHCR7, NES, DUT | CA2 1786/4885PGAM1 3060/4885TDP1 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.