Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.85 |
| ▸ | NPC1 | O15118 | 2/20 | 0.85 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.62 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2751208 | 0.93 | RAB9A (0.97) | RAB9ANPC1EPHX2SMN1; SMN2KMT2A | |
| SCHEMBL11336178 | 0.92 | RAB9A (1.00) | RAB9ANPC1EPHX2SMN1; SMN2KMT2A | |
| SCHEMBL25464439 | 0.84 | NPC1 (0.62) | RAB9ANPC1EPHX2SMN1; SMN2KMT2A | |
| SCHEMBL18657997 | 0.82 | ALDH1A1 (0.74) | RAB9ANPC1EPHX2SMN1; SMN2KMT2A | |
| SCHEMBL3189722 | 0.82 | EPHX2 (0.77) | RAB9ANPC1EPHX2 | |
| SCHEMBL3189716 | 0.82 | EPHX2 (0.77) | RAB9ANPC1EPHX2 | |
| SCHEMBL2719565 | 0.81 | EPHX2 (1.00) | RAB9ANPC1EPHX2 | |
| SCHEMBL18657813 | 0.81 | UBE2M (0.75) | RAB9ANPC1EPHX2SMN1; SMN2KMT2A | |
| SCHEMBL10458447 | 0.81 | KDM4E (0.72) | RAB9ANPC1SMN1; SMN2KMT2AHTT | |
| SCHEMBL2752438 | 0.81 | RAB9A (0.76) | RAB9ANPC1EPHX2SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283799-A | Quinazoline methionine adenosyltransferase 2A inhibitors | 南京正大天晴制药有限公司 | 2023-06-23 | — | — | CN | disclosed |