SCHEMBL2902222

SCHEMBL2902222

Fc1cc(Br)ccc1-c1nccs1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.40
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
PDPK1 O15530 1/20 0.39
ABL1 P00519 1/20 0.38
BCR P11274 1/20 0.38
FBP1 P09467 1/20 0.37
CASP6 P55212 1/20 0.36
AR P10275 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
CYP2A6 P11509 1/20 0.35
ADORA2A P29274 1/20 0.35
HSP90AA1 P07900 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
KMT2A Q03164 2/20 0.34
PKM P14618 1/20 0.34
CYP1A1 P04798 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP1B1 Q16678 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2653159 0.90 PDPK1 (0.39) F2RL1PDPK1ABL1BCRFBP1
SCHEMBL5912405 0.82 F2RL1 (0.51) F2RL1PDPK1FBP1CASP6AR
SCHEMBL12326416 0.79 SRC (0.42) F2RL1PDPK1FBP1HSP90AA1NPC1
SCHEMBL4047151 0.79 PDPK1 (0.39) F2RL1PDPK1ABL1BCRFBP1
SCHEMBL11440352 0.79 ADORA2A (0.41) F2RL1PDPK1ABL1BCRFBP1
SCHEMBL16131407 0.77 PDPK1 (0.42) F2RL1PDPK1FBP1CASP6AR
SCHEMBL16112355 0.76 MAPT (0.40) PDPK1ABL1BCRFBP1LOXL2
SCHEMBL8567274 0.76 PDPK1 (0.55) PDPK1CASP6ARLOXL2CYP2A6
SCHEMBL16990890 0.76 PDPK1 (0.56) PDPK1ABL1BCRLOXL2CYP2A6
SCHEMBL24988889 0.76 ADRB2 (0.43) F2RL1PDPK1CASP6ARLOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101501031-B Oxazolidone derivatives as PR modulators WYETH (US) 2012-02-01 CN disclosed
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD F2RL1 4182/4885ALOX5AP 1015/4885FEN1 3501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.