Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NMT1 | P30419 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25758620 | 0.97 | HTR7 (0.53) | HTR7ALDH1A1KCNH2HRH3SLC6A2 | |
| SCHEMBL30375512 | 0.94 | TAAR1 (0.53) | HTR7ALDH1A1SLC6A4HTR2ACCR3 | |
| SCHEMBL24069429 | 0.88 | SLC6A2 (0.63) | HTR7KCNH2SLC6A2SLC6A4MEN1 | |
| SCHEMBL29022586 | 0.88 | HTR7 (0.69) | HTR7ALDH1A1KCNH2HTR2ATP53 | |
| SCHEMBL30389889 | 0.86 | HTR7 (0.48) | HTR7KCNH2HRH3HTR2A | |
| SCHEMBL25290527 | 0.85 | SLC6A2 (0.59) | HTR7KCNH2SLC6A2SLC6A4MEN1 | |
| SCHEMBL25758613 | 0.84 | HTR7 (0.64) | HTR7ALDH1A1KCNH2SLC6A4HTR2A | |
| SCHEMBL25758526 | 0.82 | CCR3 (0.58) | HTR7SLC6A2SLC6A4MEN1HTT | |
| SCHEMBL25758544 | 0.82 | MEN1 (0.69) | HTR7KCNH2SLC6A2SLC6A4HTR2A | |
| SCHEMBL25758537 | 0.82 | HTR7 (0.58) | HTR7ALDH1A1SLC6A2SLC6A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | claimed |
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | disclosed |
| EP-4159718-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |