Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25758613 | 0.96 | HTR7 (0.64) | HTR7ALDH1A1TP53GAASIGMAR1 | |
| SCHEMBL24069058 | 0.90 | HTR7 (0.85) | HTR7ALDH1A1HTR1AMBTD1L3MBTL1 | |
| SCHEMBL29022575 | 0.88 | HTR7 (0.57) | HTR7ALDH1A1TP53GAASIGMAR1 | |
| SCHEMBL13889021 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TP53GAAMAPTPOLB | |
| SCHEMBL29022599 | 0.85 | HTR1A (0.74) | HTR7HTR1AKMT2AHTR2A | |
| SCHEMBL25758620 | 0.84 | HTR7 (0.53) | HTR7ALDH1A1TP53GAASIGMAR1 | |
| SCHEMBL12672472 | 0.84 | HTR7 (0.83) | HTR7ALDH1A1HTR1AMBTD1L3MBTL1 | |
| SCHEMBL24069429 | 0.83 | SLC6A2 (0.63) | HTR7SIGMAR1MAPTKMT2AKCNH2 | |
| SCHEMBL25758490 | 0.82 | HTR7 (0.72) | HTR7ALDH1A1GAASIGMAR1MAPT | |
| SCHEMBL30375512 | 0.82 | TAAR1 (0.53) | HTR7ALDH1A1HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | claimed |
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | disclosed |
| EP-4159718-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |