SCHEMBL25758620

SCHEMBL25758620

O=S(=O)(NCCCCN1CCC(CCCc2ccccc2)CC1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ HTR7 P34969 3/20 0.53
▸ ALDH1A1 P00352 2/20 0.50
▸ HTR1A P08908 1/20 0.50
▸ CCR3 P51677 1/20 0.49
▸ SIGMAR1 Q99720 1/20 0.49
▸ KCNH2 Q12809 3/20 0.48
▸ HRH3 Q9Y5N1 3/20 0.48
▸ HTR2A P28223 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ NMT1 P30419 2/20 0.48
▸ MAPT P10636 1/20 0.47
▸ CARM1 Q86X55 1/20 0.46
▸ PRMT6 Q96LA8 1/20 0.46
▸ SLC6A2 P23975 1/20 0.46
▸ SLC6A4 P31645 1/20 0.46
▸ CCR5 P51681 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29022575 0.97 HTR7 (0.57) HTR7ALDH1A1CCR3SIGMAR1KCNH2
SCHEMBL30375512 0.91 TAAR1 (0.53) HTR7ALDH1A1HTR1ACCR3HTR2A
SCHEMBL25290527 0.88 SLC6A2 (0.59) HTR7HTR1ACCR3SIGMAR1KCNH2
SCHEMBL25758613 0.88 HTR7 (0.64) HTR7ALDH1A1HTR1ASIGMAR1KCNH2
SCHEMBL24069429 0.85 SLC6A2 (0.63) HTR7CCR3SIGMAR1KCNH2MAPT
SCHEMBL29022586 0.84 HTR7 (0.69) HTR7ALDH1A1HTR1ASIGMAR1KCNH2
SCHEMBL30389889 0.84 HTR7 (0.48) HTR7HTR1AKCNH2HRH3HTR2A
SCHEMBL24069471 0.81 SIGMAR1 (0.54) CCR3SIGMAR1HRH3TP53CARM1
SCHEMBL25758458 0.80 SLC6A2 (0.61) CCR3GAAMAPTCARM1PRMT6
SCHEMBL25758526 0.79 CCR3 (0.58) HTR7HTR1ACCR3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157124-A Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-23 — — CN claimed
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 — — US disclosed
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 — — US disclosed
CN-116157124-A Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-23 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS SLC6A2, SLC6A3, SLC6A4 HTR7 79/4885ALDH1A1 1394/4885HTR1A 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback