Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.35 |
| ▸ | STK17B | O94768 | 2/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822637 | 0.81 | CYP2A6 (0.46) | CYP2A6APPADRB2HSD17B1HSD17B2 | |
| SCHEMBL288852 | 0.78 | KDM4E (0.59) | LMNAJAK2JAK3 | |
| SCHEMBL290238 | 0.78 | SMN1; SMN2 (0.56) | — | |
| SCHEMBL289837 | 0.77 | DPP4 (0.53) | LMNA | |
| SCHEMBL3828017 | 0.77 | ALDH1A1 (0.37) | TRPV3LMNA | |
| SCHEMBL2787018 | 0.76 | SMN1; SMN2 (0.41) | APPSTK17BSTK17ACAMKK1AURKB | |
| SCHEMBL26500221 | 0.75 | APP (0.45) | CYP2A6APPHSD17B1HSD17B2CYP19A1 | |
| SCHEMBL289905 | 0.75 | HPGD (0.60) | — | |
| SCHEMBL290100 | 0.75 | CYP2A6 (0.40) | CYP2A6APPADRB2HSD17B1HSD17B2 | |
| SCHEMBL5148513 | 0.74 | APP (0.57) | CYP2A6APPADRB2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |