Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30695900 | 0.77 | RCE1 (0.39) | CFTRGOPCACHEHDAC3HDAC1 | |
| SCHEMBL29177300 | 0.77 | RCE1 (0.39) | CFTRGOPCACHEHDAC3HDAC1 | |
| SCHEMBL29024288 | 0.70 | ACHE (0.41) | CFTRGOPCACHEHDAC3HDAC1 | |
| SCHEMBL12690256 | 0.69 | HCAR3 (0.34) | — | |
| SCHEMBL824021 | 0.67 | TSHR (0.32) | HDAC6 | |
| SCHEMBL13543776 | 0.65 | ACHE (0.40) | CFTRGOPCACHEMEN1KMT2A | |
| SCHEMBL10220157 | 0.65 | MEN1 (0.42) | HDAC6MEN1KMT2AMAPK1MAPT | |
| SCHEMBL12690245 | 0.65 | HCAR3 (0.40) | LMNASMN1; SMN2ADRA2B | |
| SCHEMBL12690242 | 0.65 | HCAR3 (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL28405143 | 0.63 | RCE1 (0.61) | CFTRGOPCHDAC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956070-A | Sulfonamide compounds | 阿纳克西斯制药股份有限公司 | 2023-04-11 | — | — | CN | disclosed |