Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23768153 | 0.75 | HCAR3 (0.38) | IGF1RHCRTR1 | |
| SCHEMBL29024293 | 0.70 | CFTR (0.39) | ACHES1PR3CFTRGOPCHDAC3 | |
| SCHEMBL21016980 | 0.69 | CSF1R (0.39) | HCRTR1 | |
| SCHEMBL21831103 | 0.69 | NOTUM (0.39) | HCRTR1 | |
| SCHEMBL16775795 | 0.67 | ALDH1A1 (0.43) | HCRTR1LMNADEGS1 | |
| SCHEMBL16754403 | 0.67 | ABL1 (0.42) | HCRTR1DEGS1 | |
| SCHEMBL15408413 | 0.65 | RAB9A (0.54) | HCRTR1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL21017010 | 0.65 | HCAR3 (0.38) | IGF1RHCRTR1MAPK1 | |
| SCHEMBL21016983 | 0.65 | HCRTR1 (0.33) | HCRTR1 | |
| SCHEMBL22877206 | 0.65 | HCAR3 (0.46) | HCRTR1HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956070-A | Sulfonamide compounds | 阿纳克西斯制药股份有限公司 | 2023-04-11 | — | — | CN | disclosed |