Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 11/20 | 0.79 |
| ▸ | DBF4 | Q9UBU7 | 11/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289549 | 0.89 | CDC7 (0.63) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL5733147 | 0.83 | CDC7 (1.00) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL1316281 | 0.82 | CDC7 (0.77) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL892889 | 0.82 | CDC7 (0.77) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL12034449 | 0.81 | CDC7 (0.69) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL290384 | 0.81 | CDC7 (0.75) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL2885887 | 0.80 | TRPM8 (0.78) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL4464882 | 0.80 | CDC7 (0.73) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL2823339 | 0.80 | CDC7 (0.73) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL2085303 | 0.80 | CDC7 (0.73) | CDC7DBF4KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |