Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 15/20 | 1.00 |
| ▸ | DBF4 | Q9UBU7 | 15/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289730 | 0.88 | CDC7 (0.79) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL5240574 | 0.87 | CDC7 (1.00) | CDC7DBF4KDM4ETRPM8 | |
| Hydrochloric Acid SCHEMBL289729 | 0.87 | CDC7 (0.77) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL1316281 | 0.87 | CDC7 (0.77) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL892889 | 0.87 | CDC7 (0.77) | CDC7DBF4KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11121421 | 0.86 | CDC7 (0.76) | CDC7DBF4TRPM8 | |
| SCHEMBL290384 | 0.86 | CDC7 (0.75) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL8324969 | 0.85 | CDC7 (1.00) | CDC7DBF4TRPM8 | |
| SCHEMBL2885887 | 0.84 | TRPM8 (0.78) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL2085303 | 0.84 | CDC7 (0.73) | CDC7DBF4KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6812231-B2 | INHIBITING ACTIVATED BLOOD-COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-02 | — | — | US | disclosed |
| US-20020107290-A1 | Benzamidine derivative | AJINOMOTO CO., INC. (JP) | 2002-08-08 | — | — | US | disclosed |
| US-6410538-B2 | ANTICOAGULANT OR AN AGENT FOR TREATING OR PREVENTING THROMBI OR EMBOLI | AJINOMOTO CO., INC. (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| US-20010056123-A1 | Anticoagulant or an agent for treating or preventing thrombi or emboli | AJINOMOTO CO., INC (JP) | 2001-12-27 | — | — | US | disclosed |
| CN-1311771-A | Benzamidine derivative | AJINOMOTO KK (JP) | 2001-09-05 | — | — | CN | disclosed |
| EP-1086946-A1 | BENZAMIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2001-03-28 | — | — | EP | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |
| US-4528291-A | 2-(4'-Pyridinyl)-thiazole compounds and their use in increasing cardiac contractility | SCHERING CORPORATION (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0097323-A2 | 2-(4-Pyridyl)-thiazole derivatives | SCHERING CORPORATION (US) | 1984-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107290-A1 | Benzamidine derivative | SERPINE1, SERPINC1, TFPI | CDC7 2468/4885DBF4 192/4885KDM4E 3660/4885 |
| US-20010056123-A1 | Anticoagulant or an agent for treating or preventing thrombi or emboli | SERPINC1, SERPINE1, F2 | CDC7 2732/4885DBF4 1260/4885KDM4E 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.