Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763660 | 0.82 | HTT (0.58) | THRBGAASMN1; SMN2HTTPRMT5 | |
| SCHEMBL5636028 | 0.79 | THRB (0.51) | THRBGAASMN1; SMN2HTTPRMT5 | |
| SCHEMBL7503348 | 0.79 | SMN1; SMN2 (0.53) | THRBGAASMN1; SMN2PRMT5STS | |
| SCHEMBL29024484 | 0.79 | THRB (0.52) | THRBGAASMN1; SMN2PRMT5STS | |
| SCHEMBL1493280 | 0.78 | HTT (0.54) | THRBHTTKDM4EGPR119MEN1 | |
| SCHEMBL20299835 | 0.78 | HTT (0.54) | THRBHTTKDM4EGPR119MEN1 | |
| SCHEMBL31663414 | 0.78 | HTT (0.57) | THRBHTTKDM4EGPR119MEN1 | |
| SCHEMBL5447888 | 0.78 | CCR5 (0.50) | THRBGAASMN1; SMN2PRMT5STS | |
| SCHEMBL7496661 | 0.77 | USP30 (0.54) | THRBGAASMN1; SMN2STSKDM4E | |
| SCHEMBL4343857 | 0.77 | HPGDS (0.55) | THRBGAASMN1; SMN2PRMT5STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354925-A | Pyrazole derivatives and use thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |