SCHEMBL29024967

SCHEMBL29024967

NC(=O)c1ccccc1C(=O)Nc1ccccc1.NC(=O)c1ccccc1C(N)=O.NC(=O)c1ccccc1C(N)=O.NC(=O)c1ccccc1C(N)=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.71
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
HPGD P15428 2/20 0.63
KDM4E B2RXH2 1/20 0.63
LMNA P02545 1/20 0.63
TP53 P04637 1/20 0.63
HTT P42858 1/20 0.63
HSD17B10 Q99714 1/20 0.63
TDP1 Q9NUW8 3/20 0.61
SIRT2 Q8IXJ6 3/20 0.59
METAP2 P50579 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2C9 P11712 1/20 0.59
ALOX12 P18054 1/20 0.59
CHRNB2 P17787 1/20 0.59
CHRNB4 P30926 1/20 0.59
CHRNA3 P32297 1/20 0.59
CHRNA4 P43681 1/20 0.59
PRKCI P41743 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533636 1.00 ALDH1A1 (0.71) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL1991352 1.00 ALDH1A1 (0.71) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL437231 0.89 ALDH1A1 (0.87) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL31194406 0.89 SIRT2 (0.61) ALDH1A1MEN1KMT2AHTTSIRT2
SCHEMBL11266257 0.87 ALDH1A1 (0.83) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL11266259 0.87 ALDH1A1 (0.83) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL31252862 0.87 CYP3A4 (0.74) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL28669297 0.87 CYP3A4 (0.74) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL2521357 0.87 KMT2A (0.56) ALDH1A1MEN1KMT2AHPGDKDM4E
Salicylanilide SCHEMBL6152522 0.85 MEN1 (0.83) ALDH1A1MEN1KMT2AHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112236381-B Applying micrometer diameter yarns 琳得科美国股份有限公司 2023-05-30 CN disclosed