Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.59 |
| ▸ | METAP2 | P50579 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.59 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.59 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.59 |
| ▸ | PRKCI | P41743 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533636 | 1.00 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL29024967 | 1.00 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL437231 | 0.89 | ALDH1A1 (0.87) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL31194406 | 0.89 | SIRT2 (0.61) | ALDH1A1MEN1KMT2AHTTSIRT2 | |
| SCHEMBL11266257 | 0.87 | ALDH1A1 (0.83) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL11266259 | 0.87 | ALDH1A1 (0.83) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL31252862 | 0.87 | CYP3A4 (0.74) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL28669297 | 0.87 | CYP3A4 (0.74) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL2521357 | 0.87 | KMT2A (0.56) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| Salicylanilide SCHEMBL6152522 | 0.85 | MEN1 (0.83) | ALDH1A1MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140005049-A1 | ACTIVE COMPOUND COMBINATIONS | ILG KERSTIN (DE) | 2014-01-02 | — | — | US | claimed |
| EP-2515649-A2 | ACTIVE COMPOUND COMBINATIONS | Bayer Intellectual Property GmbH (DE) | 2012-10-31 | — | — | EP | claimed |
| WO-2011080044-A2 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | claimed |
| US-20110152077-A1 | Active compound combinations | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | claimed |
| US-20140005049-A1 | ACTIVE COMPOUND COMBINATIONS | ILG KERSTIN (DE) | 2014-01-02 | — | — | US | disclosed |
| US-20140007297-A1 | BRASSICA PLANTS WITH ALTERED ARCHITECTURE | BAYER CROPSCIENCE NV (BE) | 2014-01-02 | — | — | US | disclosed |
| US-8530381-B2 | Active compound combinations | BAYER CROPSCIENCE AG (DE) | 2013-09-10 | — | — | US | disclosed |
| EP-2566318-A1 | BRASSICA PLANTS WITH ALTERED ARCHITECTURE | Bayer CropScience NV (BE) | 2013-03-13 | — | — | EP | disclosed |
| EP-2515649-A2 | ACTIVE COMPOUND COMBINATIONS | Bayer Intellectual Property GmbH (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011137998-A1 | BRASSICA PLANTS WITH ALTERED ARCHITECTURE | BAYER BIOSCIENCE N.V. (BE) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011080044-A2 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |
| US-20110152077-A1 | Active compound combinations | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
| US-4357347-A | INSECTICIDES, INSECT GROWTH REGULATORS | THE UPJOHN COMPANY (US) | 1982-11-02 | — | — | US | disclosed |
| US-4357347-A | INSECTICIDES, INSECT GROWTH REGULATORS | THE UPJOHN COMPANY (US) | 1982-11-02 | — | — | US | disclosed |
| US-4357347-A | INSECTICIDES, INSECT GROWTH REGULATORS | THE UPJOHN COMPANY (US) | 1982-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152077-A1 | Active compound combinations | BROX, ATL3, AKR7A2 | ALDH1A1 3621/4885MEN1 95/4885KMT2A 3664/4885 |
| US-20140005049-A1 | ACTIVE COMPOUND COMBINATIONS | BROX, ATL3, AKR7A2 | ALDH1A1 3621/4885MEN1 95/4885KMT2A 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.