SCHEMBL29025129

SCHEMBL29025129

Cc1cc(C)c(C(=O)c2cc(F)ccc2[P](=O)c2ccccc2)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.33
AVPR2 P30518 1/20 0.33
OXTR P30559 1/20 0.33
AVPR1A P37288 1/20 0.33
KMT2A Q03164 5/20 0.33
MEN1 O00255 4/20 0.33
HPGD P15428 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
CRHR1 P34998 2/20 0.32
TSHR P16473 2/20 0.32
GAA P10253 1/20 0.32
KEAP1 Q14145 1/20 0.32
MAOB P27338 1/20 0.32
FFAR4 Q5NUL3 1/20 0.31
P2RY4 P51582 1/20 0.31
MAPK1 P28482 1/20 0.31
DHODH Q02127 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28050538 0.88 NFE2L2 (0.40) METAP2KMT2AMEN1HPGDNPSR1
SCHEMBL4520122 0.79 KMT2A (0.38) METAP2KMT2AMEN1HPGDNPSR1
SCHEMBL29435246 0.76 KMT2A (0.43) METAP2KMT2AMEN1HPGDNPSR1
SCHEMBL3685865 0.76 KMT2A (0.43) METAP2KMT2AMEN1HPGDNPSR1
SCHEMBL22069484 0.72 KMT2A (0.35) KMT2AMEN1HPGDNPSR1LMNA
SCHEMBL28050616 0.72 POLB (0.45) NPSR1LMNASMN1; SMN2GAAMAPK1
SCHEMBL29885738 0.71 KMT2A (0.40) METAP2KMT2AMEN1HPGDNPSR1
SCHEMBL29609450 0.70 ABCB1 (0.40) METAP2KMT2AMEN1HPGDNPSR1
SCHEMBL28520511 0.70 KMT2A (0.38) METAP2KMT2AMEN1HPGDNPSR1
SCHEMBL28258477 0.70 KMT2A (0.47) METAP2KMT2AMEN1HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112279940-B Acylphosphine photoinitiator and preparation method thereof 山东科技大学 2023-06-27 CN disclosed