Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685865 | 0.83 | KMT2A (0.43) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL29435246 | 0.83 | KMT2A (0.43) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL4520122 | 0.77 | KMT2A (0.38) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL28050538 | 0.76 | NFE2L2 (0.40) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL29025129 | 0.72 | METAP2 (0.33) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL30568742 | 0.72 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2 | |
| SCHEMBL7182214 | 0.72 | HPGD (0.42) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL1138268 | 0.72 | KMT2A (0.43) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL29885738 | 0.72 | KMT2A (0.40) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL9874808 | 0.72 | KMT2A (0.40) | KMT2AMEN1HPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402829-B1 | SILICONE-COMPATIBLE COMPOUNDS | Henkel IP & Holding GmbH (DE) | 2020-06-17 | — | — | EP | disclosed |