SCHEMBL4520122

SCHEMBL4520122

Cc1cc(C)c(C(=O)c2cccc([P](=O)c3ccccc3)c2C(=O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.38
MEN1 O00255 2/20 0.38
POLB P06746 1/20 0.35
METAP2 P50579 1/20 0.35
HPGD P15428 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
CRHR1 P34998 2/20 0.33
GAA P10253 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MYC P01106 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28050538 0.82 NFE2L2 (0.40) KMT2AMEN1METAP2HPGDNPSR1
SCHEMBL29435246 0.81 KMT2A (0.43) KMT2AMEN1POLBMETAP2HPGD
SCHEMBL3685865 0.81 KMT2A (0.43) KMT2AMEN1POLBMETAP2HPGD
SCHEMBL29025129 0.79 METAP2 (0.33) KMT2AMEN1METAP2HPGDNPSR1
SCHEMBL29885738 0.79 KMT2A (0.40) KMT2AMEN1POLBMETAP2HPGD
SCHEMBL27918757 0.78 AKR1C3 (0.47) KMT2AMEN1POLBNPSR1GAA
SCHEMBL22069484 0.77 KMT2A (0.35) KMT2AMEN1HPGDNPSR1LMNA
SCHEMBL28258477 0.75 KMT2A (0.47) KMT2AMEN1POLBMETAP2HPGD
SCHEMBL21828550 0.74 CNR2 (0.38) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL7183573 0.74 KMT2A (0.39) KMT2AMEN1POLBMETAP2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9284662-B2 Soybean based fibers BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-03-15 US disclosed
US-20140100351-A1 SOYBEAN BASED FIBERS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-04-10 US disclosed
WO-2014046853-A1 SOYBEAN BASED FIBERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-03-27 WO disclosed
US-20090202714-A1 Methods of Making and using Metal Oxide Nanoparticles MANDZY NATALIA S 2009-08-13 US disclosed
WO-2006135390-A2 LENS FORMING SYSTEMS AND METHODS Q2100, INC. (US) 2006-12-21 WO disclosed
US-20060065989-A1 Lens forming systems and methods FINANCIAL RESOURCE ASSOCIATES, INC. 2006-03-30 US disclosed