Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002394 | 0.80 | HPGD (0.37) | HPGDGPR119CTSKUSP2SMN1; SMN2 | |
| SCHEMBL31715308 | 0.77 | USP2 (0.39) | HPGDCTSKUSP2SMN1; SMN2PREP | |
| SCHEMBL31322461 | 0.77 | CTSK (0.40) | HPGDCTSKUSP2SMN1; SMN2PREP | |
| SCHEMBL31357623 | 0.76 | HDAC1 (0.36) | HPGDGPR119CTSKUSP2SMN1; SMN2 | |
| SCHEMBL28730458 | 0.74 | MEN1 (0.30) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31357715 | 0.73 | ADORA1 (0.36) | HPGDGPR119CTSKUSP2SMN1; SMN2 | |
| SCHEMBL28730461 | 0.73 | HSD17B10 (0.41) | HPGDGPR119SMN1; SMN2KMT2AKDM1A | |
| SCHEMBL29993273 | 0.73 | SMN1; SMN2 (0.47) | HPGDGPR119CTSKUSP2SMN1; SMN2 | |
| SCHEMBL12350366 | 0.72 | CTSK (0.38) | HPGDCTSKUSP2SMN1; SMN2MEN1 | |
| SCHEMBL7405154 | 0.72 | USP2 (0.40) | HPGDGPR119CTSKUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114426507-B | Method for synthesizing methyl thiomethylene ester compound | 南京师范大学 | 2023-06-30 | — | — | CN | disclosed |