Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002394 | 0.92 | HPGD (0.37) | SMN1; SMN2USP2HPGDGPR119MEN1 | |
| SCHEMBL28858721 | 0.76 | GRM5 (0.34) | SMN1; SMN2USP2HPGDGPR119MEN1 | |
| SCHEMBL31715308 | 0.75 | USP2 (0.39) | SMN1; SMN2USP2HPGDMEN1KMT2A | |
| SCHEMBL31322461 | 0.75 | CTSK (0.40) | SMN1; SMN2USP2HPGDMEN1KMT2A | |
| SCHEMBL28885252 | 0.74 | USP2 (0.62) | SMN1; SMN2USP2RECQLHPGDGPR119 | |
| SCHEMBL31357623 | 0.74 | HDAC1 (0.36) | SMN1; SMN2USP2HPGDGPR119MAPT | |
| Formic Acid SCHEMBL29026228 | 0.73 | HPGD (0.34) | SMN1; SMN2USP2HPGDGPR119MAPT | |
| SCHEMBL31357715 | 0.71 | ADORA1 (0.36) | SMN1; SMN2USP2RECQLHPGDGPR119 | |
| SCHEMBL12350366 | 0.71 | CTSK (0.38) | SMN1; SMN2USP2HPGDMEN1KMT2A | |
| SCHEMBL42476 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2USP2RECQLHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440507-B | Compound as apoptosis protein inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |