Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Di(Hydroxyethyl)Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.31 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2513783 | 1.00 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| Acetic Acid SCHEMBL2515140 | 1.00 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL273034 | 0.90 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1THRB | |
| Pentaethylene Glycol SCHEMBL9614725 | 0.90 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Acetic Acid SCHEMBL775971 | 0.90 | ALDH1A1 (0.42) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| Triethylene Glycol SCHEMBL7049732 | 0.90 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL994880 | 0.90 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Acetic Acid SCHEMBL21878939 | 0.90 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Acetic Acid SCHEMBL21878891 | 0.90 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL28411928 | 0.90 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344769-A | Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element | 日产化学工业株式会社 | 2024-07-16 | — | — | CN | disclosed |
| CN-118043732-A | Weak anchoring liquid crystal aligning agent, liquid crystal display element and polymer | 日产化学株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-117460990-A | Weak anchoring liquid crystal aligning agent, liquid crystal display element and copolymer | 日产化学株式会社 | 2024-01-26 | — | — | CN | disclosed |
| CN-117186663-A | Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element | 日产化学工业株式会社 | 2023-12-08 | — | — | CN | disclosed |
| CN-108139632-B | Liquid crystal display element | 日产化学工业株式会社 | 2023-12-05 | — | — | CN | disclosed |
| CN-113167957-B | Liquid crystal aligning agent, liquid crystal alignment film, and phase difference material | 日产化学株式会社 | 2023-09-26 | — | — | CN | disclosed |
| CN-111868618-B | Liquid crystal aligning agent, polymer for obtaining the same, liquid crystal alignment film, and liquid crystal display element using the same | 日产化学株式会社 | 2023-09-22 | — | — | CN | disclosed |
| CN-111868617-B | Liquid crystal aligning agent, polymer for obtaining the same, liquid crystal alignment film, and liquid crystal display element using the same | 日产化学株式会社 | 2023-09-12 | — | — | CN | disclosed |
| CN-116507968-A | Radical generating film forming composition, radical generating film, method for manufacturing liquid crystal display element, and liquid crystal display element | 日产化学株式会社 | 2023-07-28 | — | — | CN | disclosed |
| CN-116507643-A | Radical generating film forming composition, radical generating film, method for manufacturing liquid crystal display element, and liquid crystal display element | 日产化学株式会社 | 2023-07-28 | — | — | CN | disclosed |
| CN-116323702-A | Method for producing single-layer phase difference material | 日产化学株式会社 | 2023-06-23 | — | — | CN | disclosed |