SCHEMBL2902828

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2906977	0.88	PTPN22 (0.36)	ACP1MAPK1SMN1; SMN2LMNAHTT
	SCHEMBL2906684	0.86	SMN1; SMN2 (0.39)	ACP1MAPK1SMN1; SMN2LMNAHTT
	SCHEMBL13685704	0.83	NCF1 (0.48)	MAPK1SMN1; SMN2LMNAHTTALDH1A1
	SCHEMBL2907784	0.79	NTRK1 (0.41)	MAPK1APPSMN1; SMN2LMNAHTT
	SCHEMBL2903146	0.78	POLB (0.46)	ADORA2AADORA2BMAPK1SMN1; SMN2ALDH1A1
	SCHEMBL2904762	0.78	NPC1 (0.43)	SMN1; SMN2ALDH1A1KDM4EHPGDNPC1
	SCHEMBL2908205	0.78	NPC1 (0.41)	MAPK1SMN1; SMN2LMNAHTTALDH1A1
	SCHEMBL2901754	0.78	MEN1 (0.43)	ADORA3MAPK1APPSMN1; SMN2LMNA
	SCHEMBL2907397	0.78	TRPC5 (0.37)	MAPK1SMN1; SMN2LMNAHTTALDH1A1
	SCHEMBL2908289	0.77	SGMS2 (0.47)	ADORA3ADORA2AADORA2BADORA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.