Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157760 | 1.00 | BLM (0.47) | BLMSLC1A3SLC1A2SLC1A1KDM4C | |
| SCHEMBL2904240 | 0.98 | BLM (0.48) | BLMSLC1A3SLC1A2SLC1A1KDM4C | |
| SCHEMBL18233925 | 0.93 | BLM (0.54) | BLMSLC1A3SLC1A2SLC1A1KDM4C | |
| SCHEMBL20377188 | 0.93 | BLM (0.54) | BLMSLC1A3SLC1A2SLC1A1KDM4C | |
| SCHEMBL31544402 | 0.93 | SLC1A3 (0.48) | BLMSLC1A3SLC1A2SLC1A1ACE2 | |
| SCHEMBL31544399 | 0.93 | SLC1A3 (0.48) | BLMSLC1A3SLC1A2SLC1A1ACE2 | |
| SCHEMBL16140111 | 0.91 | SLC1A3 (0.50) | BLMSLC1A3SLC1A2SLC1A1ACE2 | |
| SCHEMBL31080656 | 0.90 | KDM4C (0.51) | KDM4CKDM4APHF8KDM2AGPR84 | |
| SCHEMBL28014446 | 0.88 | BLM (0.52) | BLMSLC1A3SLC1A2SLC1A1KDM4C | |
| SCHEMBL2830699 | 0.84 | GPR84 (0.57) | ACE2GPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100322877-A1 | SILICONE ELASTOMERS IN COSMETIC ESTERS | ALZO INTERNATIONAL, INC. | 2010-12-23 | — | — | US | claimed |
| EP-2211833-A2 | SILICONE ELASTOMERS IN COSMETIC ESTERS | Alzo International, Inc. (US) | 2010-08-04 | — | — | EP | claimed |
| WO-2009054931-A2 | SILICONE ELASTOMERS IN COSMETIC ESTERS | ALZO INTERNATIONAL, INC. (US) | 2009-04-30 | — | — | WO | claimed |
| WO-2015048228-A2 | IMPROVED SILICONE ELASTOMER GELS AND RELATED HYDROSILYLATION PROCESSES | ALZO INTERNATIONAL, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| WO-2012135281-A2 | SILICONE CROSSLINKED UNSATURATED HYDROCARBON BASED POLYMERS | ALZO INTERNATIONAL, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20100322877-A1 | SILICONE ELASTOMERS IN COSMETIC ESTERS | ALZO INTERNATIONAL, INC. | 2010-12-23 | — | — | US | disclosed |
| EP-2211833-A2 | SILICONE ELASTOMERS IN COSMETIC ESTERS | Alzo International, Inc. (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009054931-A2 | SILICONE ELASTOMERS IN COSMETIC ESTERS | ALZO INTERNATIONAL, INC. (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100322877-A1 | SILICONE ELASTOMERS IN COSMETIC ESTERS | CUTA, LAGE3, MMS19 | BLM 239/4885SLC1A3 3543/4885SLC1A2 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.