Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028700 | 0.88 | MPO (0.47) | ESR2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29028724 | 0.86 | SMN1; SMN2 (0.46) | NPC1RAB9AESR2MEN1KMT2A | |
| SCHEMBL29028719 | 0.86 | MAPT (0.46) | RAB9AESR2MEN1KMT2ALMNA | |
| SCHEMBL29028787 | 0.86 | MAPT (0.46) | NPC1RAB9AESR2MEN1KMT2A | |
| SCHEMBL29028775 | 0.85 | MEN1 (0.41) | MEN1KMT2ALMNAMPOMAPT | |
| SCHEMBL30473327 | 0.85 | MEN1 (0.41) | MEN1KMT2ALMNAMPOMAPT | |
| SCHEMBL29028696 | 0.83 | CSNK2A1 (0.40) | NPC1RAB9AKMT2ASMN1; SMN2MPO | |
| SCHEMBL29028789 | 0.83 | MPO (0.39) | NPC1RAB9AESR2MEN1KMT2A | |
| SCHEMBL29028781 | 0.82 | MPO (0.47) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL29028702 | 0.82 | RAB9A (0.47) | RAB9AESR2MEN1KMT2AMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |