Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 3/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028722 | 0.86 | CTSK (0.46) | MAPTNPSR1ADORA3MEN1KMT2A | |
| SCHEMBL29028719 | 0.85 | MAPT (0.46) | RAB9AMAPTL3MBTL1PDPK1KDM4E | |
| SCHEMBL29028700 | 0.84 | MPO (0.47) | MAPTL3MBTL1KDM4ENPSR1ESR2 | |
| SCHEMBL29028680 | 0.82 | NPC1 (0.43) | RAB9AMAPTPDPK1KDM4EESR2 | |
| SCHEMBL29028724 | 0.82 | SMN1; SMN2 (0.46) | RAB9AMAPTNPSR1ADORA3ESR2 | |
| SCHEMBL29028787 | 0.82 | MAPT (0.46) | RAB9AMAPTHIF1AKDM4EADORA3 | |
| SCHEMBL29028789 | 0.80 | MPO (0.39) | RAB9AMAPTL3MBTL1PDPK1KDM4E | |
| SCHEMBL29028781 | 0.79 | MPO (0.47) | RAB9AMAPTHIF1AADORA3MPO | |
| SCHEMBL28748645 | 0.78 | CYP2C9 (0.47) | RAB9ACTDSP1MAPTL3MBTL1HIF1A | |
| SCHEMBL1921069 | 0.77 | L3MBTL1 (0.45) | RAB9ACTDSP1MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |